Bion

BioN­Tech has signed an agree­ment with No­var­tis to ex­pand fill-fin­ish sup­port for the com­pa­ny’s Covid-19 vac­cine — made in col­lab­o­ra­tion with Pfiz­er in Slove­nia.

The Ljubl­jana, Slove­nia ster­ile man­u­fac­tur­ing site will be used to fill at least 24 mil­lion dos­es in 2022, and un­der the terms of the agree­ment, No­var­tis will take bulk mR­NA ac­tive in­gre­di­ent from BioN­Tech, fill that in­to vials, and ship it back to them for dis­tri­b­u­tion.

The agree­ment fol­lows one signed ear­li­er this year, when No­var­tis start­ed fill­ing for BioN­Tech at its Stein site in Switzer­land in June af­ter gain­ing ap­proval from the EMA.

“No­var­tis con­tin­ues to of­fer its world-class ca­pa­bil­i­ties to oth­er com­pa­nies to take over man­u­fac­tur­ing ac­tiv­i­ties in­clud­ing a va­ri­ety of tech­nolo­gies such as mR­NA pro­duc­tion and oth­ers,” the com­pa­ny said in a state­ment. “The specifics will be dis­closed when we con­clude spe­cif­ic agree­ments.”

Exacis links with CCRM for NK ther­a­pies

An im­muno-on­col­o­gy com­pa­ny based out of Cam­bridge, MA an­nounced a part­ner­ship with the Toron­to-based Cen­tre for Com­mer­cial­iza­tion of Re­gen­er­a­tive Med­i­cine Thurs­day to man­u­fac­ture mR­NA-en­gi­neered nat­ur­al killer cell prod­ucts.

Exacis Bio­ther­a­peu­tics will al­so re­ceive a cash in­vest­ment from CCRM En­ter­pris­es Hold­ings, the for-prof­it arm of CCRM.

“We wel­come CCRM as a key part­ner to al­low us to rapid­ly ad­vance our virus-free man­u­fac­tur­ing process­es to make nov­el NK cell prod­ucts that are en­gi­neered for per­for­mance and to avoid re­jec­tion. CCRM is a rec­og­nized leader in iP­SC-de­rived cell ther­a­py de­vel­op­ment and man­u­fac­tur­ing and we are thrilled to have them as a part­ner,” Exacis CEO Gre­go­ry Fiore said in a state­ment.

Found­ed just last year, Exacis is fo­cused on en­gi­neer­ing off-the-shelf NK and T-cell ther­a­pies that tar­get hema­to­log­ic ma­lig­nan­cies and sol­id tu­mors.

New South Wales to spend $95M on mR­NA man­u­fac­tur­ing

The gov­ern­ment in New South Wales is look­ing to cre­ate a na­tion­al hub for mR­NA vac­cine pro­duc­tion.

Pre­mier Do­minic Per­rot­tet said that the gov­ern­ment will spend $95 mil­lion in a part­ner­ship with the new RNA Bio­sciences Al­liance, which is made up of all the uni­ver­si­ties in NSW.

“We are the first state in Aus­tralia to de­liv­er a pi­lot man­u­fac­tur­ing fa­cil­i­ty to spear­head the es­tab­lish­ment of a lo­cal RNA in­dus­try,” Per­rot­tet said. “The COVID pan­dem­ic has demon­strat­ed to the world that it is crit­i­cal­ly im­por­tant that we have the ca­pa­bil­i­ty to de­vel­op vac­cines quick­ly and for our coun­try to have sov­er­eign ca­pa­bil­i­ty.”

The fa­cil­i­ty will make a po­ten­tial mR­NA man­u­fac­tur­ing in­dus­try pos­si­ble do­mes­ti­cal­ly and gives the po­ten­tial for the fa­cil­i­ty to scale up and down as need­ed for fu­ture pan­demics.

Source : https://endpts.com/novartis-expands-manufacturing-with-pfizer-and-biontech-exacis-links-with-ccrm-for-nk-cell-therapies/

758
No­var­tis ex­pands man­u­fac­tur­ing with Pfiz­er and BioN­Tech; Exacis links with CCRM for NK cell ther­a­pies

Source:ENDPOINTS NEWS

No­var­tis ex­pands man­u­fac­tur­ing with Pfiz­er and BioN­Tech; Exacis links with CCRM for NK cell ther­a­pies

J&J pro­pos­es slid­ing boost­er time­lines as FDA ques­tions lack of da­ta for Delta, old­er adults be­fore ad­comm

Source:ENDPOINTS NEWS

J&J pro­pos­es slid­ing boost­er time­lines as FDA ques­tions lack of da­ta for Delta, old­er adults be­fore ad­comm

Chinook Therapeutics Announces Upcoming Data Presentations and Investor Conference Call During ...

Source:Associated Press

Chinook Therapeutics Announces Upcoming Data Presentations and Investor Conference Call During ...

Tipper Body Market Development Analysis 2021: Report Holds Unique Research on Industry Size, Share, Growth, Revenue and Forecast to 2026

Source:MarketWatch

Tipper Body Market Development Analysis 2021: Report Holds Unique Research on Industry Size, Share, Growth, Revenue and Forecast to 2026

Bion to Develop Sustainable Beef Production Demonstration Facility

Source:WFMZ-TV

Bion to Develop Sustainable Beef Production Demonstration Facility